농약
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작성일 24-04-26 22:33
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순서
5.6.3 유기인계 살충제
최초: tetraethyl pyrophosphate (TEPP): very effective
단점: highly toxic to mammals LD50 mice (oral) 2 mg/kg
unstable in water
대체품: parathion, paraoxon
advantage(장점) : broad spectrum; low volatility; not persistent; stable in water
단점: high mammalian toxicity
저독성 대체품: fenitrothion (ref. p594 표 5.6.1)
mechanism of toxic action: AChE inhibition
toxic sign: Ach accumulation에 기인
Ach의 muscarine 증상: 구토, 복통, 설사, 배변, 축동, 유연, 유루, 기관지수축, 기관지분비 증대
Ach의 nicotine 증상: 피로, 근력저하, 전신성 경련, 호흡곤란, cyanosis
해독제: atropine (cholinergic inhibitor),
2-PAM (pralidoxime) (AChE 저해작용을 해제)
parathion → paraoxon [metabolic activation; metabolic intoxication]
① metabolic activation (toxification)
paraoxon: AchE 저해작용② ③ ④ ⑤ : metabolic detoxification
A…(skip)⑤ is the main detoxification process catalyzed by esterase found in almost every tissue.
레포트/기타
농약
,기타,레포트
5-6농약-wd , 농약기타레포트 ,
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5-6농약-wd
설명
다.
